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Volume 12, Issue 4, Pages 455-463 (May 2008)


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Acute stress response and recovery after whiplash injuries. A one-year prospective study

Alice KongstedaCorresponding Author Informationemail address, Tom Bendixb, Erisela Qeramacd, Helge Kaschcd, Flemming W. Bachcd, Lars Korsholme, Troels S. Jensencd

Received 3 October 2006; received in revised form 29 June 2007; accepted 9 July 2007. published online 27 September 2007.

Abstract 

Chronic whiplash-associated disorder (WAD) represents a major medical and psycho-social problem. The typical symptomatology presented in WAD is to some extent similar to symptoms of post traumatic stress disorder. In this study we examined if the acute stress reaction following a whiplash injury predicted long-term sequelae. Participants with acute whiplash-associated symptoms after a motor vehicle accident were recruited from emergency units and general practitioners. The predictor variable was the sum score of the impact of event scale (IES) completed within 10 days after the accident. The main outcome-measures were neck pain and headache, neck disability, general health, and working ability one year after the accident. A total of 737 participants were included and completed the IES, and 668 (91%) participated in the 1-year follow-up. A baseline IES-score denoting a moderate to severe stress response was obtained by 13% of the participants. This was associated with increased risk of considerable persistent pain (OR=3.3; 1.8–5.9), neck disability (OR=3.2; 1.7–6.0), reduced working ability (OR=2.8; 1.6–4.9), and lowered self-reported general health one year after the accident. These associations were modified by baseline neck pain intensity. It was not possible to distinguish between participants who recovered and those who did not by means of the IES (AUC=0.6). In conclusion, the association between the acute stress reaction and persistent WAD suggests that post traumatic stress reaction may be important to consider in the early management of whiplash injury. However, the emotional response did not predict chronicity in individuals.

a The Back Research Center Part of Clinical Locomotion Science, Backcenter Funen, University of Southern Denmark, Funen Hospital Ringe, Lindevej 5, DK-5750 Ringe, Denmark

b Institutes of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark

c Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark

d Department of Neurology, Aarhus University Hospital, Aarhus, Denmark

e Department of Statistics, University of Southern Denmark, Odense, Denmark

Corresponding Author InformationCorresponding author. Tel.: +45 6362 1848; fax: +45 6362 1839.

PII: S1090-3801(07)00598-8

doi:10.1016/j.ejpain.2007.07.008


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